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Birthmark Hemangiomas Associated SyndromesThe PHACE (Posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta, cardiac defects, and eye anomalies) refers to infants with large plaque hemangiomas involving the head and neck region associated with brain, cardiovascular, and eye anomalies. Hemangiomas of infancy can be seen as part of multiple hamartoma syndromes such as Proteus syndrome and Bannayan-Riley-Ruvalcaba syndrome. |