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Epidermal Sebaceous Cyst Potential to RuptureCysts frequently develop in areas of friction. Most epidermal cysts arise from the squamous epithelium of the hair follicle. Unlike pilar cysts, the epidermal cyst wall is fairly delicate and thus prone to rupture. Rupture is followed by foreign body reaction to keratin extruded into the dermis and acute inflammation. Such lesions appear to be infected. However, cultures are usually sterile. |