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Sexually transmitted infections

Genital Warts HPV Bowenoid Papulosis STD

Intraepithelial neoplasia: bowenoid papulosis

Bowenoid papulosis are lesions associated with oncogenic HPV types, most commonly HPV 16 but many other HPV types have been implicated. Lesions show atypical cells in the full thickness of the epithelium.

Bowenoid papulosis occurs in young sexually active persons most often between the ages of 25 and 35 years. The disease tends to be benign and spontaneous regression can occur in several months. Lesion may persist for years in older individuals. Most lesions are asymptomatic.

Bowenoid papulosis presents as solitary or multiple, small, red, brown, or flesh-colored papules with a flat or verrucous surface. Papules can coalesce into larger plaques. They are most often found on the shaft of the penis or the external genitalia of females, but they can occur anywhere on the genitalia and in the perianal region. Warts, molluscum contagiosum, seborrheic keratosis and squamous cell carcinoma may have a similar appearance. Treatment with scissor excision , electrodesiccation, cryosurgery, laser surgery, or with topical medications such as podophyllum, topical 5-fluorouracil or imiquimod (Aldara).