• Alopecia
• Acniform eruptions
• Benign tumors
• Bullous diseases
• Dermoscopy
• Nevi, melanoma
• Nonmelanoma cancer
• Psoriasis and others
• Stds
• Vascular tumors
• Vulvar disease

• Herpes simplex
• Genital Herpes Simplex Introduction STD
• Genital Herpes Simplex Risk factors and Rate of Transmission
• Previous HSV type 1 infection
• Genital Herpes Simplex Primary and Recurrent Infections
• Genital Herpes Simplex Signs and Symptoms
• Genital Herpes Simplex Latency and Reactivation STD
• Genital Herpes Simplex Recurrent Infection STD
• Genital Herpes Simplex Frequency of Recurrence
• Genital Herpes Simplex Anatomic Site
• Genital Herpes Simplex Asymptomatic transmission
• Genital Herpes Simplex Prevention
• Genital Herpes Simplex Laboratory diagnosis
• Genital Herpes Simplex Serology
• Genital Herpes Simplex Testing Pregnant Women
• Genital Herpes Simplex Monogamous Couples
• Genital Herpes Simplex STD Treatment
• Genital Herpes Simplex Daily Treatment Suppressive Therapy
• Genital Herpes Simplex During Pregnancy
• Warts (HPV infection)
• Genital Warts HPV Introduction and Causes STD
• Genital Warts HPV Screening Tests
• Genital Warts HPV Interpretation of Test Results
• Genital Warts HPV The HPV DNA Test
• Genital Warts HPV Lesion and Location
• Genital Warts HPV Lesion Types STD
• Genital Warts HPV Subclinical Lesions
• Genital Warts HPV Bowenoid Papulosis STD
• Genital Warts HPV Clinical Evaluation STD
• Genital Warts HPV Differential diagnosis
• Genital Warts HPV Treatment STD
• Genital Warts HPV Treatment Approach to Therapy
• Molluscum Contagiosum
• Molluscum Contagiosum STD Introduction
• Molluscum Contagiosum Clinical manifestations
• Molluscum Contagiosum Diagnosis
• Molluscum Contagiosum Treatment
• Syphilis
• Syphilis Epidemiology STD
• Syphilis Treponema Pallidum
• Syphilis Causes STD
• Incubating Syphilis
• Secondary Syphilis STD
• Syphilis Latency
• Congenital Syphilis
• Early Congenital Syphilis
• Late Congenital Syphilis
• Syphilis Laboratory Diagnosis
• Syphilis Serologic Tests
• Syphilis Nontreponemal Reaginic Tests
• Syphilis Specific Treponemal Tests
• False-Positive Serologic Test for Syphilis
• Syphilis Treatment STD
• Chancroid
• Chancroid STD Introduction
• Chancroid Clinical presentation
• Chancroid Diagnosis
• Chancroid Treatment STD
• Chancroid Syndromic management
• Lymphogranuloma venereum
• Lymphogranuloma Venereum STD Introduction
• Lymphogranuloma Venereum Clinical features
• Lymphogranuloma Venereum Laboratory diagnosis
• Lymphogranuloma Venereum Treatment
• Donovanosis (granuloma inguinale)
• Donovanosis Granuloma Inguinale STD Introduction
• Donovanosis Granuloma Inguinale STD Clinical apperances
• Donovanosis Granuloma Inguinale STD Diagnostic tests
• Donovanosis Granuloma Inguinale STD Treatment

Late Congenital Syphilis

Late congenital syphilis

Symptoms and signs of late congenital syphilis become evident after age 5 years. The average age at first diagnosis is 30 years. It may be difficult to distinguish from acquired syphilis.

The child may appear to recover from the early lesions, but during second dentition or puberty the disease reappears. Development is arrested or retarded, and the child takes on a shriveled or withered appearance, and presents a stunted growth. Brain development is retarded. The testicles are atrophied or infantile. The most important signs are (bony prominences of the forehead) (frontal bossae) (87%), saddle nose (74%), short poorly developed maxilla (83%) and high arched palate (76%). Mulberry molars have more than four small cusps on a narrow first lower molar of the second dentition. Pegged shaped, lateral incisors and notched central incisors along the cutting edge give the permanent incisors a screwdriver like shape. This is called Hutchinson's sign. Hutchinson's teeth appear after age 6 years. Higoumenakis sign is unilateral enlargement of the sternoclavicular portion of the clavicle as an end result of periostitis (39%). Rhagades are linear scars radiating from the angle of the eyes, nose, mouth, and anus (8%). Keratitis develops first in one eye, then in the other. This begins as a hazy condition, and may result in permanent impaired vision, or, after a long period, may gradually clear up, with a complete restoration of sight. Iritis also frequently occurs.

Hutchinson's triad is Hutchinson's teeth, interstitial keratitis, and VIIIth nerve deafness and is considered pathognomonic of late congenital syphilis.

Other late characteristic stigmata include recurrent arthropathy and bilateral knee effusions (Cluttons joints).

Because at least one third of the mothers who give birth to syphilitic children have had prenatal care and about half have had a nonreactive serologic test during the first trimester of pregnancy, serologic testing is always warranted at the time of delivery, especially in high-risk patients. All neonates born to syphilitic mothers should be treated, regardless of whether the mother was treated during her pregnancy.