Warts appear as isolated small papules or may be grouped closely together and form a mass that covers a wide area. The lesions are flesh colored or red. Warts may be flat and difficult to detect even by careful physical examination. Warts may be florid when they appear in moist intertriginous areas such as around the anus or the vulva. These extensive lesions are best treated with the careful application of topical medicines. Warts are occasionally found in the oral cavity. Consider testing all patients with any sexually transmitted diseases for HIV infection.