Early Lyme disease is treated with doxycycline, amoxicillin or cefuroxime. Patient’s who are unable to tolerate any of these medications are treated with erythromycin, azithromycin or clarithromycin. Many physicians prescribe one of these antibiotics to be taken for 21 days however a ten-day course is sufficient. Nonsteroidal anti-inflammatory drugs (NSAIDs) provide effective relief of symptoms. Many of these are available as over-the-counter medications. Commonly used NSAIDs include aspirin, ibuprofen and naproxen.
The treatment of late stage Lyme disease is complicated and is often performed by infectious disease specialists.