Video Topics

Extramammary Paget’s Disease Treatment and Apperance

The disease in males and females appears as a unilateral, white-to-red, scaling or macerated, infiltrated, eroded, or ulcerated plaque, most frequently observed on the labia majora and scrotum. Persistent itching and burning is common. The clinical presentation closely resembles lichen sclerosus et atrophicus, lichen simplex chronicus, leukoplakia, or chronic yeast infection. The epidermis is infiltrated with malignant cells that migrate laterally. Conventional surgical excision or Mohs micrographic surgery, followed optionally by radiation therapy, is the treatment for regionally confined disease.