Dermnet Videos
Nonmelanoma skin cancers Videos
- Basal Cell Nevus Syndrome
- Mohs’s Micrographic Surgery
- Sclerosing or Morpheaform Basal Cell Carcinoma
- Skin Cancer Basal Cell Carcinoma
- Skin Cancer Basal Cell Carcinoma Histology
- Skin Cancer Basal Cell Carcinoma Superficial Basal Cell Carcinoma
- Skin Cancer Basal Cell Carcinoma Treatment
- Skin Cancer Nodular Basal Cell Carcinoma
- Skin Cancer Pigmented Basal Cell Carcinoma
- Skin Cancer Cutaneous T-cell Lymphoma Definition and Description
- Skin Cancer Cutaneous T-cell Lymphoma Erythrodermic stage (Sezary syndrome)
- Skin Cancer Cutaneous T-cell Lymphoma Hematology and pathology
- Skin Cancer Cutaneous T-cell Lymphoma Patch Stage
- Skin Cancer Cutaneous T-cell Lymphoma Plaque stage
- Skin Cancer Cutaneous T-cell Lymphoma Stages
- Skin Cancer Cutaneous T-cell Lymphoma Treatment
- Skin Cancer Cutaneous T-cell Lymphoma Tumor stage
- Skin Cancer Squamous Cell Carcinoma
- Skin Cancer Squamous Cell Carcinoma Appearance
- Skin Cancer Squamous Cell Carcinoma Keratoacanthoma Variant
- Skin Cancer Squamous Cell Carcinoma of the Arms and Legs
- Skin Cancer Squamous Cell Carcinoma Relationship to HPV
- Skin Cancer Squamous Cell Carcinoma Transplant Patients
- Skin Cancer Squamous Cell Carcinoma Treatment
Video Topics
Skin Cancer Squamous Cell Carcinoma Appearance
SCCs arising from actinic keratoses may have a thick, adherent scale. The tumor is soft and freely movable and may have a red, inflamed base. These lesions are most frequently observed on the bald scalp, forehead and backs of the hands. Cutaneous horns may begin as actinic keratoses and degenerate into SCC.
SCCs originating on the lip or from apparently normal skin are aggressive and metastasize to the regional lymph nodes and beyond.
Those SCCs beginning in actinically damaged skin, but not from actinic keratoses, appear as firm, movable, elevated masses with a sharply defined border and little surface scale.
The potential for SCCs to metastasize is related to the size, location, degree of differentiation, histologic evidence of perineural involvement, immunologic status and depth of invasion. SCCs that arise in actinically damaged skin were previously thought to have a minimal potential for metastasis; however, such lesions may be aggressive. SCC first metastasizes to regional lymph nodes in the majority of cases.