Lichen Sclerosus Treatment | Dermatology Education Lichen Sclerosus Treatment Video
January 18, 2022

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Lichen Sclerosus Treatment

Advise gentle cleansing of involved areas using Cetaphil cleanser, wearing of ventilated cotton underwear and liberal use of bland emollients and lubricants. Avoid panty liners, pre-mixed douches and sprays, and scented toilet paper.

Topical application of group V steroid creams for 2 weeks is initial treatment for uncomplicated skin lesions and prepubertal mucosal lesions. Clobetasol propionate 0.05% (is effective for vaginal and penile disease in adults. Intralesional triamcinolone is useful for unresponsive areas.

Tacrolimus ointment (Protopic) 0.1% may be of help in treating vaginal or penile disease.

Testosterone propionate 2% ointment has been used for years. Many experts now doubt its effectiveness. Topical 5-fluorouracil with carbon dioxide laser has been used for penile lesions with some success.

Acitretin (20 to 30 mg/day for 16 weeks) may be considered in severe cases. Selected refractory medical cases may benefit from surgical reconstruction of scarred areas.